Configuring QuickBooks Database Server Manager involves several key steps for optimal performance. Start by downloading the installer from the official Intuit website. Run the installation wizard, selecting the Custom option for a tailored setup. Choose the installation location, ensuring it aligns with your server setup. After installation, open the program and scan your company files. Set up and manage users with appropriate permissions. Verify that the database server manager is running, allowing multi-user access. Lastly, regularly update the software to ensure compatibility and access new features.